Expression Profiling
Gene expression profiling simultaneously compares the expression levels of many genes between two or more sample types. This analysis can help scientists identify the molecular basis for phenotypic differences and select gene expression targets for in-depth study using other technologies. Gene expression profiling provides valuable insight into the role of differential gene expression in normal biological and disease processes. There are many techniques used for gene expression profiling. One of the major techniques for expression profiling includes Measuring Relative Activity by SAGE and Super SAGE, where SAGE stands for serial analysis of gene expression technology for the analysis of expressed genes. The other technique includes Gene annotation which provides functional and other information, for example the location of each gene within a particular chromosome. Some functional annotations are more reliable than others; some are absent. Gene annotation databases change regularly, and various databases refer to the same protein by different names, reflecting a changing understanding of protein function. Having identified some set of regulated genes, the next step in expression profiling involves looking for patterns within the regulated set for categorizing regulated genes. This can be done by finding similarities between the functioning of the proteins produced from different cell. Further categorization is done on the basis of relationship between two genes and their products by finding patterns among regulated genes. This is analysed by the fact that what these regulated genes actually are and what they do. Compared to Proteomics, the human genome contains on the order of 25,000 genes which work in concert to produce on the order of 1,000,000 distinct proteins. Knowledge of the precise proteins a cell makes, is more relevant than knowing how much messenger RNA is made from each gene, gene expression profiling provides the most global picture possible in a single experiment.
Gene Expression profiling has a growing research being utilized by major companies like Wafergen Biosystems, Afymetrix, SBI, Luminex, Asper Biotech, Genentech San Francisco to name a few. The research has been supported as a course by more than 470 universities and gains international funding too.
Relevant Conferences:
2nd International Conference on Genetic and Protein Engineering, Nov 14-16, 2016, Atlanta, USA; Clinical and Molecular Genetics November 28-30, 2016 Chicago, USA; 5th International Conference and Exhibition on Cell and Gene Therapy May 19-21, 2016 San Antonio, USA; International Conference on Genetic Counselling and Genomic Medicine August 11-12, 2016 Birmingham, UK; 6th International Conference on Bioinformatics March 29-30, 2016 Valencia, Spain; 6th International Conference & Expo on Proteomics March 31-Apr 2, 2016, Atlanta, USA; NGS 2016 Genome Annotation, April 4-6, 2016, Barcelona, Spain; NGS Data Analysis and Informatics Conference, February 18-19, 2016, San Diego, USA; Post-Transcriptional Gene Regulation (GRS), July 9-10, 2016, Vermont, United States; Basic Epigenetic Mechanisms in Cancer, November 8–11, 2015, Berlin, Germany; Keystone Symposia: Metabolism, Transcription and Disease, Jan 10-14, 2016, Utah, USA.
- SAGE and SuperSAGE
- Gene annotation
- Categorizing Regulated Genes
- Finding Patterns among Regulated Genes
- Comparison to Proteomics
Related Conference of Expression Profiling
16th International Conference on Tissue Science and Regenerative Medicine
15th International Conference on Biofuels and Bioenergy
6th Annual Next Generation Sequencing Asia Congress
International Conference on Genome Editing and Gene Modulation Congress
Genome Editing and Gene Modulation Congress 2016
International Conference on Understanding the Function of Human Genome Variation
18th International Conference on Proteomics and Bioinformatics
Quantitative Proteomics and Data Analysis
FEBS Workshop on Chromatin Proteomics
3rd Conference on Protein and Proteomics
International Conference on Transcription and Chromatin
Pichia 2016 Protein Expression Conference
Basic Epigenetic Mechanisms in Cancer
Post-Transcriptional Gene Regulation
NGS Data Analysis and Informatics Conference
NGS 2016 Genome Annotation
International Conference on Metabolism Transcription and Disease
Expression Profiling Conference Speakers
Recommended Sessions
- Cancer Transcriptomics: Integrative & Computational Approaches
- Clinical Applications & Related Disorders
- Diagnosis & Applications of RNA-Seq
- Epigenetics
- Exploring Transcriptome
- Expression Profiling
- Human Transcriptomics
- NGS Technologies
- Ocular Transcriptomics
- Relation with OMICS Sciences
- RNA Editing & Interference: Interplay
- Single Cell Transcriptomics
- Transcriptional Regulation & Attenuation
- Transcriptome analysis & Gene Expression
- Transcriptome Technologies Market
- Transcriptomics & Proteomics in Microorganisms
- Transcriptomics & Proteomics in Plants
- Transcriptomics Case Reports
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