Yongyan Sun
Chinese Academy of Sciences, China
Title: Application of Transcriptomics on study of biological effects of magnetic field exposure
Biography
Biography: Yongyan Sun
Abstract
Transcriptomics is one of functional genomic approaches widely applied in life science research in recent years. Based on the background of crosses and integration between environmental science and life science subjects, growing cutting-edged molecular technologies such as proteomics, metabolomics and etc., are applied in studying environmental problems, especially exploring biological relationships between human living environments and health. Electromagnetic environment is one of extensively existed urban environmental factors in modern life during the development of urbanization and modernization. Thus, it is indispensable and inevitable to investigate the biological effects of electromagnetic field (EMF) on human health and disease. Transcriptomic analysis, which could to some extent reflect the gene expression alteration under EMF exposure, is rewarding to much deeper understanding on molecular mechanism of living organism sensing and responsing to EMF exposure. In our study, we have explored the bio-effects of extremely low-frequency electromagnetic field (ELF-EMF) and radio frequency electromagnetic field (RF-EMF) via transcriptomic analysis on model organism, such as Saccharomyces cerevisiae, Drosophila melanogaster and Caenorhabditis elegans. Several results indicate that the living organism indeed response to EMF exposure and different model organism showed changes in various ways. Therefore, the utilization of transcriptomic approach on studying the health effect of EMF exposure lays the molecular basis for further research on mechanism of electromagnetic field sensing and responsing.