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An Yuan Guo


An Yuan Guo

Huazhong University of Science and Technology, China

Biography

An Yuan Guo has completed his PhD from Peking University and Post-doctoral studies from VCU and Vanderbilt University. His research focuses on the transcription factor and ncRNA regulatory network in complex diseases with NGS data and bioinformatics database construction. He is an expert in bioinformatics database and developed a serial of databases (AnimalTFDB, miRNASNP and lncRNASNP). He developed an approach to study the microRNA and TF co-regulatory network in complex diseases. He has published about 50 papers in Molecular Psychiatry, Cancer Research, NAR, Bioinformatics, Briefings in Bioinformatics, Human Mutation etc and served as an Editor of Scientific Reports.

Abstract

Abstract : Regulatory network analysis reveals miR-146b-5p within BCR-ABL1–positive microvesicles promotes leukemic transformation of hematopoietic cells