Transcriptomics

Genomics, Proteomics and Bioinformatics

Genomics, Proteomics and Bioinformatics are all from the field of Omics scinces, which revolves around Transcriptomics. Disruptions or changes at any step of gene expression are responsible for many genetic diseases. Through the use of Genome Analysis and Microarrays scientists can determine – in a single experiment – the expression levels of hundreds or thousands of genes within a cell. All these genome sequence data can be recalled Big Data Mining. Other field of genomics related to sequence analysis is Functional Genomics, Computational Genetics, Comparative Genomics, Translational Genomics, and Evolutionary Genomics. Molecular evidence from a sequence-based application is a main agenda in Plant Genomics and Microbial Genomics. For a higher resolution of cellular differences and a better understanding of the function of an individual cell in the context of its microenvironment, Single Cell Genome sequencing is done which examines the sequence information from individual cells with optimized next generation sequencing (NGS) technologies. For more information about the products (proteins) of these cells, it is mandatory to understand the mechanism involved in their transcription and translation. In that case Proteomics of Transcription Machinery, proving itself helpful in explaining the expression of proteins by through ribosome in a Single cell. Coming to the Bioinformatics, the major breakthrough involves Drug designing and Drug Discovery, making the entire process more fast at quite low cost. Genomic labs have the fastest growing market with nearly 250 universities concentrating on its research majorly to be named Whitetail Genetic Research Institute, Stanford University, National Human Genome Research Institute. Major companies concentrating on the research are Affymetrix, Applied Biosystems, Foster City, and Genentech etc. Drug Discovery research has the major growing market with applications in pharmaceuticals and medicine and thus major companies like Bristol-Myers Squibb Company, Isis Pharmaceuticals, Inc. , Merck & Co. Inc. and Johnson & Johnson focusing on the growing industry.